Cushing's Syndrome (Fragile Skin Syndrome) muImbwa

Muviri wembwa yakasarudzika system ine akawanda biochemical maitiro. Chiyero chekukura kwepanyama uye kwepfungwa kwemhuka kunoenderana nehutano hwavo. Iro hormonal background inokonzerwa nekushanda kwakakodzera kwenhengo dzomukati dzomukati. Uye kana kukanganisa kwe endocrine kukaitika, imbwa inogona kuwana Cushing's syndrome.

Zvinokonzera chirwere

Cushing's syndrome mumbwa ndeimwe yeakajairika mahomoni kusagadzikana. Nezvo, kune kuwedzera kuumbwa kweglucocorticoids inogadzirwa neadrenal glands. Kazhinji, imbwa dzakura kupfuura makore manomwe dzinotambura nechirwere ichi, asi imbwa diki dzinogonawo kukanganiswa. Zvikonzero zvikuru zvechirwere ndezvi:

1. Mamota epituitary gland. Inomira kubudisa hormone ACTH muhuwandu hwakakodzera uye haigoni kudzora chiyero che cortisol muropa. Iyi fomu ye fragile skin syndrome inowanikwa mu85-90% yembwa. 

2. Mamota eadrenal glands. Muchiitiko ichi, kuwanda kwe cortisol kunogadzirwa apo imbwa inopinda mumamiriro ezvinhu akaoma uye inotya zvikuru. Kuwedzera kana kushaikwa kwecortisol inzira yakananga yekukura kwezvakakomba pathologies mumuviri wemhuka. Pathology yeadrenal glands inowanzoitika muimbwa dzakura pamakore 11-12 ezera. 

3. Sekondari shanduko (iatrogenic hyperadrenocorticism). Zvinoitika nekuda kwekugara kwenguva refu kurapwa kweallergies, dermatitis uye kuzvimba kwakanyanya nemadosi makuru emishonga yehomoni kubva kuboka reglucocorticoid.

Nzira yekuziva nekurapa Cushing's syndrome

Chirwere chinotanga nezviratidzo zvinonyatsozivikanwa:

• kudonha nguva dzose, umo imbwa isingagoni kushivirira uye kuita weti kumba;
• nyota yakasimba uye isingadzimiki;
• kushaya simba, kupera simba, kusafarira, kurara;
• kuwedzera kudya nekudya kunyange zvinhu zvisingadyiwi;
• dumbu rinoputika nekuda kwemusuru atrophy;
• kuparara kwebvudzi padumbu uye kumativi;
• kuderedza uremu kana kuwedzera uremu nekudya kwakajairwa;
• kusava nekubatana;
• hormonal disruptions: kumisa estrus muvakadzi uye atrophy ye testicles muvarume;
• kuchinja maitiro: imbwa ine rudo inotya, ine hasha.

Chirwere ichi chinonyengera, sezvo chichiperekedzwa nematambudziko akasiyana-siyana: arterial hypertension, zvirwere zveitsvo uye urinary turakiti, chirwere cheshuga mellitus, osteoporosis, kusagadzikana munhengo dzekubereka. 

Mhuka dzakadai semufudzi, dachshund, beagle, terrier, poodle, labrador, boxer inotarirwa nechirwere cheCushing, saka varidzi vanofanira kuongororwa nguva nenguva kuti vaonekwe kwechirwere ichi. Kazhinji, chirwere chinobata imbwa dzemarudzi makuru anorema kupfuura 20 kg. Kuongororwa kunoitwa nachiremba wemhuka uye kunogona kusanganisira kuongororwa kwemuviri, kuongororwa kwekiriniki uye biochemical ropa, urinalysis, X-rays, MRI yepituitary uye adrenal glands, ultrasound, uye kuongorora bvunzo kuona huwandu hwecortisol muropa. Pakurapa, chiremba wemhuka anoshandisa nzira dzekurapa uye dzekuvhiya:

1. Muchiitiko chekutanga, chiremba anogona kuraira kurapwa kwezvinodhaka kudzora mazinga ecortisol. 

2. Muchiitiko chechipiri, anogona kubvisa imwe kana maviri adrenal glands uye kuisa imbwa pahomoni therapy.

Muzviitiko zvakanyanyisa, chiremba wemhuka anogona kupa kurapa kwehupenyu hwose. Chiratidzo chekupora kwechipfuwo kuderera kwechido uye kunwa mvura kwakajairika. Kana kurapa kusina kutanga munguva, imbwa inogona kufa nekuneta. 

Munhu angabatwa nechirwere cheCushing here?

Chirwere cheCushing chinogona kubata kwete imbwa nekatsi chete, asiwo vanhu, asi hachisi chirwere chinopararira. Makiriniki ekuratidzwa kwechirwere mumbwa uye vanhu akafanana zvikuru: muvanhu, kufutisa kwepamuviri kunoitikawo, kuchinja kweganda uye muscle atrophy inooneka. Kana chirwere chacho chitangwa, munhu anogona kurasikirwa netsandanyama nemapfupa, oita hypertension, type 2 chirwere cheshuga, uye kutapukirwa nezvirwere zvisingawanzoitiki. Kune vana nevechiri kuyaruka, iyi inguva isingawanzo kuongororwa.

Chirwere cheCushing chakasiyana sei mumakati nembwa?

Kusiyana nembwa, Cushing's syndrome haiwanzoitika mumakati. 

• Imwe yemisiyano mukuratidzwa kwekiriniki yechirwere ichi chirwere cheshuga chisingatarisirwi zvakanaka chine insulin yakasimba kuramba. Ganda rinova rakatetepa uye risina kusimba, kati inokurumidza kupera uremu. 

• Musiyano wechipiri ndewebvudzi risina kukura mushure mekugera, mhanza mumuswe uye inosvava. 

• Musiyano wechitatu muchirwere ndiko kuumbwa kweganda calcifications mumbwa pamutsipa uye nzeve, izvo hazviitike mumakati.

Nzira yekudzivirira zvirwere

Chete iatrogenic fomu yeCushing's disease mumbwa inogona kudzivirirwa nechiyero chepakati chemishonga yehomoni mukurapa. Hazvina mhosva iwe unofanirwa kupa kurapa kwakadaro iwe pachako - unofanira kupasa miedzo yose uye kubvunzurudza chiremba wemhuka. Chero zvazvingava, varidzi vanofanira kutarisa mamiriro ejasi rembwa, kuchinja kwechido, kuwedzera nyota uye kurasikirwa kwebvudzi, uye kana zviratidzo zvikaonekwa, taura nekiriniki yemhuka. Zvese zviratidzo izvi zvichabatsira kuziva chirwere nenguva uye kuchengetedza chipfuyo chine hutano uye mhenyu kwemamwe makore akati wandei.